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王明贵
王明贵,男,博士,教授,华山医院抗生素研究所所长。

主要课程:

研究生课程《感染性疾病的抗菌药物治疗》

实践性教学:

作为博士生导师,近五年培养博士研究生18名。

学术研究课题

1.课题负责人,王明贵,国家自然科学基金,“肺炎克雷伯菌对替加环素的新耐药机制研究”(No814732502015.1-2018.12

2.课题负责人,王明贵,上海市科委基础研究重点项目,“肠杆菌科细菌对碳青霉烯类的耐药及传播机制”(No12JC14017002013.1-2015.12

3. 课题负责人,王明贵,国家自然科学基金重大项目,“革兰阴性杆菌的质粒介导耐药机制研究”(No811201080242012.1-2016.12

学术论文:

1.Chinese XDR Consensus Working Group, Guan X, He L, Hu B, Hu J, Huang X, Lai G, Li Y, Liu Y, Ni Y, Qiu H, Shao Z, Shi Y, Wang M(通讯作者), Wang R, Wu D, Xie C, Xu Y, Yang F, Yu K, Yu Y, Zhang J, Zhuo C. Laboratory diagnosis, clinical management and infection control of the infections caused by extensively drug resistant gram-negative bacilli: A Chinese consensus statement. Clin Microbiol Infect. 2015, Nov 25 Epub. doi: 10.1016/j.cmi.2015.11.004.

2.Sheng Z-K, Wang W, Guo Q, Xu X, Wang M, Yang Y, Wang M(通讯作者). Emergence of tigecycline- and carbapenem-non-susceptible Klebsiella pneumoniae ST11 clone in patients without exposure to tigecycline. J Microbiol Immunol Infect. 2015, Nov 19 Epub. doi: 10.1016/j.jmii.2015.10.014.

3.Chen M, Guo Q, Wang Y, Zou Y, Wang G, Zhang X, Xu X, Zhao M, Hu F, Qu D, Chen M, Wang M(通讯作者). Shifts in the antibiotic susceptibility, serogroups, and clonal complexes of Neisseria meningitidis in Shanghai, China: a time trend analysis of the pre-quinolone and quinolone eras. PLoS Med. 2015, 12(6): e1001838. 
4.Ding B, Hu F, Yang Y, Guo Q, Huang J, Wang M(通讯作者). Four Carbapenem-resistant Gram-negative Species Carrying Distinct Carbapenemases in a Single Patient. J Clin Microbiol. 2015, 53(3): 1031-1033. 
5.Ma Y, Xu X, Guo Q, Wang P, Wang W, Wang M(通讯作者). Characterization of fosA5, a new plasmid-mediated fosfomycin resistance gene in Escherichia coli. Lett Appl Microbiol. 2015, 60(3): 259-264. 
6.Sheng ZK, Hu F, Wang W, Guo Q, Chen Z, Xu X, Zhu D, Wang M(通讯作者). Mechanisms of tigecycline resistance among Klebsiella pneumoniae clinical isolates. Antimicrob Agents Chemother. 2014, 58(11): 6982-6985.
7.Wang W, Guo Q, Xu X, Sheng ZK, Ye X, Wang M(通讯作者). High-level tetracycline resistance mediated by efflux pumps Tet(A) and Tet(A)-1 with two start codons. J Med Microbiol. 2014, 63(Pt 11): 1454-1459. 
8.Huang J, Wang M, Ding H, Ye M, Hu F, Guo Q, Xu X, Wang M(通讯作者). New Delhi metallo-β-Lactamase-1 in carbapenem-resistant Salmonella strain, China. Emerg Infect Dis. 2013, 19(12): 2049-2051. 

9.Guo Q, Wang P, Ma Y, Yang Y, Ye X, Wang M(通讯作者). Co-production of SFO-1 and DHA-1 β-lactamases and 16S rRNA methylase ArmA in clinical isolates of Klebsiella pneumoniae. J Antimicrob Chemother. 2012, 67(10):2361-2366.

10.Yuan J, Xu X, Guo Q, Zhao X, Ye X, Guo Q, Wang M(通讯作者). Prevalence of the oqxAB gene complex in Klebsiella pneumoniae and Escherichia coli clinical isolates. J Antimicrob Chemother. 2012, 67(7): 1655-1659.

获得的学术研究表彰/奖励:

1.“临床重要耐药菌的发生和传播新机制及临床应用”2015年获教育部科技进步二等奖(第三完成人),卓超,宗志勇,王明贵,郑波,蓝乐夫,郭庆兰,钟南山。

2.一种检测肺炎支原体耐药突变的方法. 第二十七届上海市优秀发明选拔赛银奖. 2015. 徐晓刚,刘杨,王明贵